Drinking Amount Associated with Abnormal Gamma-Glutamyl Transpeptidase Expression in Women

Drinking Amount Associated with Abnormal Gamma-Glutamyl Transpeptidase Expression in Women

BACKGROUND This study investigated whether there is any difference in drinking amount associated with abnormal expression of gamma-glutamyl transpeptidase (GGT), one of the biological markers of excessive drinking, between flushing and non-flushing women after drinking. METHODS The subjects were 797 women aged 20-59 years old who visited health promotion center of Chungnam National University...

Gamma-glutamyl transpeptidase in cancer diagnosis.

Serum gamma-glutamyl transpeptidase ( G G T ), alkaline phosphatase (A L P ) and aspartate aminotransferase (A ST) were assayed in patients with cancer. GGT was more sensitive than either ALP or AST in detecting metastatic car­ cinoma to the liver in both icteric and anicteric patients with cancer. Extremely high activities of GGT were seen in patients with hepatoma, carcinoma of the pancreas a...

Gamma-glutamyl transpeptidase--its role in hepatocarcinogenesis.

Introduction The enzyme gamma-glutamyl transpeptidase (GGT)* is widely used as a marker in preneoplastic lesions in the liver during chemical carcinogenesis (1). The discovery of a link between GGT and liver carcinogenesis first occurred in 1972 when Fiala and co-workers reported elevated levels of the enzyme in livers of rats fed the hepatocarcinogen 3'-methyl-4dimethylaminoazobenzene and also...

Gamma-glutamyl-transpeptidase in myocardial infarction. Clinical and experimental studies.

Gamma-glutamyl Transpeptidase Activity in Human Fetal Lung-derived Cells

Gamma-glutamyl transpeptidase (GGT, EC 2.3.2.2) a membrane-associated enzyme is a main regulator of glutathione (GSH) levels. The enzyme is not only the inhibitor of apoptosis induced by oxidative stress, but it is engaged in anti-tumor drug cell resistance and is considered as a marker for neoplastic changes, cell differentiation and aging. The surface and total activities of GGT in unfixed, f...